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Biotech / Medical
Immunomedics (IMMU)
An SI Board Since July 1996
Posts SubjectMarks Bans Symbol
371 27 0 IMMU
Emcee:  Josh C. Pleasure, M.D. Type:  Unmoderated
A company I am really excited about with innovative technology, proven results and a genius (Dr. David M. Goldenberg) for a CEO: Immunomedics. If immunomedics continues to be as successful as they have been up until now, there will be a paradigm shift in nuclear medicine - both in diagnosis and treatment. In short Immunomedics uses monoclonal antibodies directed at granulocytes or CEA to image cancer or infection. They use technetium (or ytrium ?) labeled CEA to TREAT cancers (phase III trials in advanced ovarian CA had promising results including a 5 month complete remission which is unheard of in adv. ovarian CA). This technology is important because the antibody fragment labeling makes it more specific leading to better diagnosis, and because the antibody concentrates the isotope at the tumor site, the dose for treatment can be increased with less effect on normal tissues.

Immunomedics (IMMU) is a company on the cutting edge of immunotherapy and antibody directed imaging using Tc-99m labeled monoclonal antibody fragments. For those of you who are not familiar with these terms, Tc-99m is the most widely used radioactive isotope used in nuclear medicine imaging (eg, bone scans use Tc-99m labeled MDP). Immunomedics makes a monoclonal (ie, very specific) antibody fragment which, when injected, attaches itself to whatever the antigen (the target) is. They have an antibody fragment which is directed towards CEA. CEA is a molecule found on many types of cancer cells including breast, ovarian, colon, liver, etc.

Immunomedics recently got FDA approval for Tc-99m labeled mAB to CEA for staging colorectal cancer (one of the top 5 types of cancer). Mallinckrodt will distribute "CEA Scan" for Immunomedics. Immunomedics predicts CEA scan alone will make them profitable within 18 months.

Immunomedics also makes monoclonal antibody fragments which target white blood cells (Leukoscan) and can be used to image infections like osteomyelitis (bone infections) and appendicitis. A recent study came out showing 87% specificity for detecting appendicitis. Any of you surgeons out there know that making a definitive diagnosis of appendicitis or being able to exclude it would help in making treatment decisions. Immunomedics' agent is superior to the current wbc scan - you don't have to wait 24 hours to make a diagnosis. ALso, (you didn't hear this here) it has been shown to be more sensitive and specific than standard WBC scans.

Further points: (Taken verbatim from Dow Jones News Retrieval) 1) Preclinical data presented by Dr. Griffiths of Immunomedics suggests that Y-90-hLL2 (another compound make by IMMU) may be a promising agent for the therapy of non-Hodgkin's lymphomas (probably 50,000 cases a year) 2) Immunomedics said results of a phase I study suggest its MN-14, an anti-CEA monoclonal antibody, may be a potential agent for treating ovarian cancer (about 10,000 cases per year in US)
Immunomedics stock price can be expected to jump when the FDA approves Leukoscan - it will replace standard WBC scans which are less specific, less sensitive and require 24 hrs vs. Leukoscan's 2-3 hours.
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371same bs for 7 years. the fact you've been wasting time here goes to show thaTheRooster-11/12/2013
370still nothing new in IMMU. the only ones who prop the stock up are newbies that TheRooster-11/12/2013
369This Is a much better board, nobody to control the board so all the proper inforTheRooster-11/12/2013
368Wolve: I was looking over the bans on the other SI board and you're the onlerickerickson-4/22/2007
367No Yahoo Boards at all,and,funny how the whole world seems just a bit more peacewolverin35_42-1/19/2007
366Bill: No news that I know of. If you've been in since '99, you probablyerickerickson-12/21/2006
365Any news on the activity today, Thursday, Dec 21? Moving right along, up 8% or billapple-12/21/2006
364Larry, While I dont blame you for the response, I would not take it to personal.wolverin35_42-10/5/2006
363ERICKSON, get a life. You are some control freak who obviously needs a power trilarrylarrison-10/5/2006
362You might want to look at the news for stage one clinical trials for hgsi, aids wolverin35_42-9/29/2006
361People get tossed for repeatedly violating the TOU. Goodbye, again.SI Dave-9/29/2006
360As they say not moderated, but nice I.D., did you think of that all on your own.wolverin35_42-9/29/2006
359<i>>So, here is how things work on SI boards and IMMU. 1-anyone who poCheeky Kid-9/28/2006
358So, here is how things work on SI boards and IMMU. 1-anyone who posts contrary FUwolve-9/28/2006
357I think the change should come from the outside in and not replace doc, for examwolverin35_42-9/26/2006
356So the truth is finally out. I don't see this as a material fact, it's kdd999-9/26/2006
355Hello kdd, It was the re pore from the other board, not limited to the vile remawolverin35_42-9/25/2006
354wolve, if it's the real wolv sorry I said you were fake, but I don't rekdd999-9/25/2006
353Bone man, if you are the original? (i really don't know) You were the funniewolverin35_42-9/23/2006
352kd, I always liked your post, even the ones, "not on topic" that can gwolverin35_42-9/23/2006
351Hey Erick. I can not believe you let brown, from the other board get away with wolverin35_42-9/23/2006
350SIadmin (Dave) has a quick trigger finger for spam and insulting posts.tom pope-9/14/2006
349i like the idea fellas - having a civil discussion on the yahoo boards is so flutbone0096-9/14/2006
348Eric, I see you can get 5 posts per day with a free membership on this board. kdd999-9/9/2006
347There's some discussion over on the iVillage message board, which I'm terickerickson-9/2/2006
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