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Biotech / Medical
Madrigal Pharmaceuticals
An SI Board Since April 2018
Posts SubjectMarks Bans Symbol
138 12 0 MDGL
Emcee:  Lynn Type:  Moderated
"Madrigal Pharmaceuticals, Inc. (Nasdaq: MDGL) is a clinical-stage biopharmaceutical company pursuing novel therapeutics that target a specific thyroid hormone receptor pathway in the liver, which is a key regulatory mechanism common to a spectrum of cardio-metabolic and fatty liver diseases with high unmet medical need. The company’s lead candidate, MGL-3196, is a first-in-class, orally administered, small-molecule, liver-directed, thyroid hormone receptor (THR) ß-selective agonist in clinical development for the treatment of non-alcoholic steatohepatitis (NASH) and familial dyslipidemias/hypercholesterolemias, among other related indications. [source:]"

MDGL has been up well over 600% the past year!

Besides discussion and new on MDGL, discussion of other pharmaceudicals working on NASH is welcome. Some of these are VKTX, GLMD, ICPT , GNFTF , GILD, and PFE (for which there is a thread here at SI).
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138Secondary offer by Bay City Capital, 1.38M shares (25% of their holding); finanMiljenko Zuanic-12/10/2019
137OT: GLMD I will not complain about recent stock move, but..... SCD1 and THR-betaMiljenko Zuanic-12/4/2019
136OT: GLMD All my attempt to gain info on Aramchol failed. So, this is next move..Miljenko Zuanic-11/26/2019
135OT: GLMD Disclosure In last few weeks I almost double (from 6K shares to 11K shaMiljenko Zuanic-11/22/2019
134RE: VKTX It is not that they did not disclosed, they did not run-it, so max humaMiljenko Zuanic-11/19/2019
133Their failure to disclose that animal tox data is why I never have owned VKTX intuck-11/19/2019
1325 & 10 mg QD. I did not expect anything. Let them disclose animal tox data, Miljenko Zuanic-11/19/2019
131What dosing arms were you expecting in the phase-2b?DewDiligence_on_SI-11/19/2019
130RE: VK28909, P2b <The study will target enrollment of approximately 340 patieMiljenko Zuanic-11/19/2019
129NASH blood test diagnostic from Genfit: Seems that... "“Miljenko Zuanic111/10/2019
128A competitor stumbles: NGM's 24 week data show beneficial effect on LFC weaktuck-10/7/2019
127OT: GLMD Aramchol p3/4 trial design similar to MGL-3196, but with FREEDOM to havMiljenko Zuanic-9/26/2019
126Has MDGL said anything about their or others' progress in developing non-invkeokalani'nui-9/22/2019
125Oral GLP-1 agonist approval significantly alter landscape for any future NASH drMiljenko Zuanic29/20/2019
124I think that Pinnacle is main (master) CRO, and sites that are controlled by theMiljenko Zuanic-8/7/2019
123We got the regular BS this morning. NCT03900429 still showing only Pinnacle as tuck-8/7/2019
122Today it was @83...suckers....Miljenko Zuanic-7/26/2019
121Friedman want to sell company and he screwed up, so Investors are thirsty for sMiljenko Zuanic-7/22/2019
120I'd prefer your scenario, but I'm not really expecting anything other thtuck-7/22/2019
119I do not like that $70! :-( I hope it may recover after 2Q report, to 120-30 levMiljenko Zuanic-7/22/2019
118Good color regarding exposure, thanks. Technically, breaking down and may see mtuck-7/22/2019
117<about my very poor judgement > on company and managements....and first orMiljenko Zuanic-7/22/2019
116I am concerned about many thinks,.... but most of all about my very poor judgemetuck-7/22/2019
115I am concerned about many thinks,.... but most of all about my very poor judgemeMiljenko Zuanic-7/22/2019
114<5.Biopsy-proven NASH (Baseline liver biopsy) based on a liver biopsy obtaineMiljenko Zuanic-7/20/2019
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