Silicon Investor - NNVC Keeping it real board for pro and con discussions

[Savant] Boston, MA -- ( ReleaseWire) -- 04/09/2020 --BIOXYTRAN, INC., a developmental st...

Savant — 4/20/2020 10:15:21 AM

Boston, MA -- ( ReleaseWire) -- 04/09/2020 --BIOXYTRAN, INC., a developmental stage biotechnology company with a pipeline of anti-necrosis drugs designed to treat hypoxia by delivering a nanoscale oxygen carrier to affected tissues in the brain, heart, lungs, and other vital organs is announcing the launch of a new presentation detailing the expected mechanism of action between BXT-10 and COVID-19 in order to reduce the viral load.

Presentation Link:
uploads-ssl.webflow.com

Over the past decade there has been a strong body of evidence that indicates that Galectin-1 is implicated in viral pathogenesis. The journal article titled Galectin-1 binds to influenza virus and ameliorates influenza virus pathogenesis demonstrates how viral pathogenesis is dependent upon galectin-1 in preclinical studies. The article demonstrated the direct binding of galectin-1 to the influenza virus. Yang et. al. indicated that "intranasal treatment of galectin-1 could enhance survival of mice against lethal challenge with influenza virus by reducing viral load, inflammation, and apoptosis in the lung." This galectin-1 treatment resulted in a survival benefit of the mice and indicated theoretical mechanisms of action (MOA) in humans.

The journal article titled Crystal Structure of Bovine Coronavirus Spike Protein Lectin Domain explored the evolution of the coronavirus N-terminal domains (NTDs) which are commonly referred to as coronavirus protein spikes. Guiguing Peng et. al. concluded that "Bovine coronavirus NTD shares structural folds and sugar-binding sites with human galectins and has subtle yet functionally important differences from protein-binding NTD of mouse coronavirus." This study confirmed the linkage between the mouse coronavirus and humans. There is much evidence to show that the coronavirus can jump between species. Since this receptor is similar on both species there is a consensus among the Scientific advisory board that this will translate to efficacy in humans.

The 2015 article titled, Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural Studies demonstrated the similarities between influenza and SARS. Dr Fang Li said "the following evolutionary scenario has been proposed for coronavirus S1-NTDs. Through gene capture, ancestral coronaviruses might have acquired a host galectin, which would become the S1-NTD of their spikes. Consequently, coronaviruses would recognize sugar receptors for cell entry." Analysis of the crystalline structures showed the linkage between influenza and SARS. COVID-19 is also known as SARS-CoV2 which is indicative that it is a subspecies of SARS. The SARS virus has a "galectin fold" which in theory represents a binding spot on the virus for Bioxytran's galectin-1 inhibitor.

"The journal articles provide a strong foundation that galectin-1 is implicated in COVID-19," said CEO David Platt of Bioxytran Inc. and co-author of Galectin. "It is clear in preclinical studies that galectin-1 was implicated in pathogenesis of the virus in mice. Further study showed that the mice share the same N-terminal domain as humans. There are also many similarities between SARS and COVID-19 because they share the similar N-terminal domain. Based on these linkages the scientific team at Bioxytran formed its thesis that a galectin-1 inhibitor could bind to the coronavirus spikes and reduce viral load. With the proper funding the company could be in human trials shortly."

releasewire.com

[HardToFind] Favipiravir Caveats en.wikipedia.org In 2014, Japan approved Favipiravir for t...

HardToFind — 4/7/2020 8:58:57 PM

Favipiravir Caveats

en.wikipedia.org

In 2014, Japan approved Favipiravir for treating viral strains unresponsive to current antivirals. Toyama Chemical initially hoped that Favipiravir would become a new influenza drug that could replace Tamiflu. However, animal experiments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health, Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in Japan.

In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Favipiravir in the treatment of influenza.

On 15 March 2020 the drug was approved in China with the name Favilavir for the treatment of influenza. The drug was also approved for use in clinical trials for treating coronavirus disease 2019 pneumonia.

On 22 March 2020 Italy has approved the drug for experimental use against COVID-19 and has begun conducting trials in 3 regions most affected by the disease. The Italian Pharmaceutical Agency, however, has reminded the public that the existing evidence in support of this drug is scant and preliminary.

[This does seem like the ideal time to experiment with its use...a worldwide pandemic largely affecting elderly people (not of child-bearing age). God help us all...]

[Savant] the Japanese are in later-phase trials of a drug which has reportedly shown prom...

Savant — 4/7/2020 12:35:02 PM

the Japanese are in later-phase trials of a drug which has reportedly shown promise. Favipiravir, manufactured by Fujifilm Toyama Chemical, has been used in China, with the Chinese officials – not normally prone to promoting Japan – stating that the antiviral drug is acting on the novel coronavirus in the way it has acted on other viruses, which is to say it is dramatically reducing the severity and duration of symptoms. The Chinese medical community tests demonstrated that treatment with the drug reduced average infection time following diagnosis from eleven days to four.

[Savant] J&J has lead candidate vaccine, plus 2 backups...Phase one not until Sept 2020....

Savant — 4/4/2020 1:03:59 PM

J&J has lead candidate vaccine, plus 2 backups...Phase one not until Sept 2020...and if successful, only emergency use in early 2021...hmm, what constitutes an emergency..*rhetorical

https://www.jnj.com/johnson-johnson-announces-a-lead-vaccine-candidate-for-covid-19-landmark-new-partnership-with-u-s-department-of-health-human-services-and-commitment-to-supply-one-billion-vaccines-worldwide-for-emergency-pandemic-use?

[Savant] Kim's human trials to start in April..

Savant — 3/4/2020 10:23:50 AM

[NewMoney_812] Good point.

NewMoney_812 — 3/4/2020 9:41:03 AM

[arvitar] "Kim, who developed MERS vaccines, Zika virus infection vaccines and Ebola vacc...

arvitar — 2/26/2020 2:40:59 PM

"Kim, who developed MERS vaccines, Zika virus infection vaccines and Ebola vaccines, is a world-renowned scientist recognized in the global pharmaceutical and bio industries,"

Compare and contrast with :

"Diwan, who has never developed anything in his entire life, and has no education or training remotely related to virology or developing drugs, has been claiming to have cured the near totality of all lethal viral infections for the last 15 years."

Someone like Kim can get funding. Diwan wouldn't even last long enough to get laughed at by the scientific review boards who advise these agencies.

[NewMoney_812] That’s interesting. NNVC should make some calls and see if they can get some fun...

NewMoney_812 — 2/26/2020 12:29:10 PM

That’s interesting. NNVC should make some calls and see if they can get some funding. I would love to see this platform actually work believe it or not. All bullshit aside, if it worked it would be an amazing benefit to mankind, and the raging bulls could finally make bank.

[Savant] A Korean scientist in the U.S. has completed the development of the coronavirus,...

Savant — 2/21/2020 10:10:22 AM

A Korean scientist in the U.S. has completed the development of the coronavirus, and has begun testing animals. The U.S. Food and Drug Administration (FDA) will conduct a clinical test on people in June after receiving a quick licensing procedure. By the end of the year, it will be possible to vaccinate Korona19 like a flu shot.

"We have already developed a DNA vaccine to prevent new virus infections that started in Wuhan, China," said Joseph Kim, 51, CEO of Inobio, a U.S. bio company, in an interview with Dong-A Ilbo in Seoul on Wednesday. "We plan to start clinical trials in the U.S. as early as June after testing animals." Kim, who developed MERS vaccines, Zika virus infection vaccines and Ebola vaccines, is a world-renowned scientist recognized in the global pharmaceutical and bio industries, with Microsoft founder Bill Gates discussing vaccine development whenever a new infectious disease occurs. The CEPI, an international private organization that participated in the Bill and Melinda Gates Foundation and Welcome Trust, signed a $9 million contract with Inobio on June 23 to develop the Korona19 vaccine

[Savant] Remdesivir, developed by Gilead Sciences, was last week given to US patient whos...

Savant — 2/3/2020 11:48:13 AM

Remdesivir, developed by Gilead Sciences, was last week given to US patient whose condition appeared to improve within a day

[Savant] msn.com and 'potential' therapy....over 2 months, if at all

Savant — 1/31/2020 6:22:14 PM

[investolator2000] Congratulations to you also. I noticed on iHub how no one listen to what you had...

investolator2000 — 1/28/2020 6:52:13 PM

Congratulations to you also. I noticed on iHub how no one listen to what you had to say. I feel good that I sold when I did instead of being one of those buying, thinking the run would continue for weeks if not months. Runs like these only last a few days at most.

[NewMoney_812] Wise. Congratulations. I made enough in the last several days trading the fiftee...

NewMoney_812 — 1/28/2020 10:51:08 AM

Wise. Congratulations. I made enough in the last several days trading the fifteen minute chart on this to pay for my new Silverado. And then buy another one. I sincerely tried to convince some of the old long term bag holders to take advantage but got snarky replies. Some people just shouldn’t invest their own money and should just buy a mutual fund.

I’ll say one thing, on the last trade I bet way more than I should have around $8 and held it over the weekend and sold at $15. That was the second Silverado. It made for a very long and slightly intoxicated weekend. NNVC had me very excited and I would have never imagined that would happen.

It’s over now. I’m done with it.

[investolator2000] Out of NNVC with just over 100% profit. Best of luck to all still in. Hope you s...

investolator2000 — 1/21/2020 6:21:43 PM

Out of NNVC with just over 100% profit. Best of luck to all still in. Hope you see green continue. Hope all have a great evening.

[HardToFind] Yes, it's been an expensive education... Never invest where management are croo...

HardToFind — 10/26/2019 6:43:31 PM

Yes, it's been an expensive education...

Never invest where management are crooks...no matter how good the potential upside.

[NewMoney_812] Ok all mean spirited bashing aside for a moment, I’ll be quick because being an ...

NewMoney_812 — 10/5/2019 12:54:07 AM

Ok all mean spirited bashing aside for a moment, I’ll be quick because being an asshole is in my nature, I like being right but I am sincerely sorry for all the lost savings and shattered dreams. It’s a hard lesson that I learned a long time ago.

Sometimes an apparent ally is a sheep in wolves clothing.

Good luck to all you guys on the bulls board. Except the wolves. You know who you are.

Apparently so does everyone else.

[NewMoney_812] Wow. The promo team is still hard at work on this insider enrichment scheme I se...

NewMoney_812 — 9/27/2019 9:21:00 PM

Wow. The promo team is still hard at work on this insider enrichment scheme I see. Not surprising.
Lawyers coming into the picture now, the interesting thing is these scam artists will defend themselves from their victims with those same victims own stolen money.

Perfect.

[investolator2000] NanoViricides, Inc. Announces One-for-Twenty Reverse Stock Split SHELTON, ...

investolator2000 — 9/12/2019 6:44:54 PM

NanoViricides, Inc. Announces One-for-Twenty Reverse Stock Split

SHELTON, Conn., Sept. 12, 2019 /PRNewswire/ -- NanoViricides, Inc. (NYSE Amer.: NNVC) (the "Company"), announced today that its Board of Directors has approved a 1-for-20 reverse split of all of the Company's capital stock, including its common stock, which will be effective after the market closes on September 23, 2019. The common stock will begin trading on a split-adjusted basis on September 24, 2019.

[Kirk ©] Wow, one year since the last post. I got out last year at 58¢ Today it is le...

Kirk © — 5/8/2019 3:53:23 PM

Wow, one year since the last post.

I got out last year at 58¢

Today it is less than half that..... 25¢ (down 57%)

If the other board goes quiet for awhile.......

[invest07] Is it not strange to see a couple of posters here who have promoted scam stocks ...

invest07 — 5/8/2018 12:57:29 PM

Is it not strange to see a couple of posters here who have promoted scam stocks in the past, or were associated with scammers, bashing a current legitimate stock ?

[arvitar] After blowing 13 years and burning through $90M, the company hasn't even identi...

arvitar — 4/6/2018 3:00:10 PM

After blowing 13 years and burning through $90M, the company hasn't even identified its first lead molecule.

During that time, the founders have paid themselves tens of millions of dollars through their Theracour laundry machine.

If you believe these clowns aren't scammers, and actually have a snowball's chance in hell of having made "the largest advance since the discovery and development of antibiotics" (with less than a year before they become insolvent, according to their latest 10-Q), then I have to doubt you really made it through medical school, unless it was somewhere in the Bahamas.

[dr.sands] NNVC is a long shot but if it can get its first product FDA approved, this will ...

dr.sands — 4/6/2018 2:48:40 PM

NNVC is a long shot but if it can get its first product FDA approved, this will be the largest advance in medicine since the discovery and development of antibiotics.

Art Sands MD

[NewMoney_812] Low 70's Yikes! To the PM I recently received, you're welcome. I'm glad some wer...

NewMoney_812 — 4/3/2018 12:36:33 PM

Low 70's Yikes! To the PM I recently received, you're welcome. I'm glad some were able to get out higher. Remember Pump Terminator was alleged to be an insider or in direct contact with an insider and saw this coming miles away.

To those that are still holding and hoping, I am truly sorry for the losses on your books, but eventually, when this is a forgotten one cent or less penny stock, 70 cents will be a long gone wished for selling point.

Good luck.

[NewMoney_812] Uh oh....now the market makers are colluding. ROFL!

NewMoney_812 — 3/13/2018 10:00:28 PM

[NewMoney_812] It’s actually getting sad to watch. The end game always looks the same on these ...

NewMoney_812 — 3/8/2018 8:14:12 PM

It’s actually getting sad to watch. The end game always looks the same on these scams, the once loyal longs are now attacking each other.

I am sincerely sorry they have been so complete swindled by the old standard “It’s not illegal to fail” stock milking scheme.

This will happen over and over and over because so many have not learned that “hope” is not a strategy or due diligence.

Sad...

[NewMoney_812] The crushing decline continues as one of the most massive bull markets in histor...

NewMoney_812 — 1/12/2018 10:24:27 PM

The crushing decline continues as one of the most massive bull markets in history also continues. I have a large tax bill this year thanks to selling into it 50% of almost everything I've held for the last 1-2 years.

Beware the promoters who are dumping their compensation shares and killing the rallies as they blow smoke up your ass.

Rock on.

[NewMoney_812] Don’t say I didn’t warn ya.

NewMoney_812 — 10/23/2017 11:09:42 PM

[Kirk ©] Someone seems to have tired of waiting for Godot, er the CEO letter reporting an...

Kirk © — 10/3/2016 12:22:28 PM

Someone seems to have tired of waiting for Godot, er the CEO letter reporting any real progress:

Thomson Reuters/Verus downgrades NANOVIRICIDES INC from HOLD to SELL.

BY Investars Analyst Actions - public
— 11:20 AM ET 10/03/2016

On October 3, 2016 Thomson Reuters/Verus downgraded NANOVIRICIDES INC ( NNVC) from HOLD to SELL.

Can't argue that the overwhelming lack of new information is good news.

[invest07] Yes, very funny. He is a real clown isn't he?

invest07 — 8/26/2016 10:52:36 AM

[drkaz] Now that's funny! Does that somehow legitimize the criminal scumbags shilling fo...

drkaz — 7/18/2016 1:20:21 AM

Now that's funny!

Does that somehow legitimize the criminal scumbags shilling for NNVC?

It would,.... if the premise of your question was even remotely correct,..... but since it is not,.... well,....

[arvitar] Serious question. And? Does that somehow legitimize the criminal scumbags ...

arvitar — 7/17/2016 7:46:27 PM

Serious question.

And? Does that somehow legitimize the criminal scumbags shilling for NNVC?

[invest07] Rawnoc, NewMoney, and their fellow scammer Brig88 are getting their asses busted...

invest07 — 7/17/2016 4:45:24 PM

Rawnoc, NewMoney, and their fellow scammer Brig88 are getting their asses busted on other boards. Is that why they have gone underground on this one,lol?

[invest07] Even more bombshells have been dropped about the short cabal scammers over there...

invest07 — 4/21/2016 3:56:08 PM

Even more bombshells have been dropped about the short cabal scammers over there. Some of them are hilarious and even criminal accusations.

[invest07] I checked the Yahoo board a few days ago and a bombshell was exploded about a se...

invest07 — 3/5/2016 7:58:17 PM

I checked the Yahoo board a few days ago and a bombshell was exploded about a sexual predator. Of course it fits right in with all other facts.

[invest07] Sorry, unlike stock board scammers I have a day job. That's why I don't eat and ...

invest07 — 2/20/2016 7:13:31 PM

Sorry, unlike stock board scammers I have a day job. That's why I don't eat and sleep on a stock board seven days a week as you and partner do. I actually contribute to society. And you?

[invest07] Oh the IRON (sic) of a magic formula to turn trash into liquid gold,ROFLMAO!!!!!...

invest07 — 2/20/2016 7:08:50 PM

Oh the IRON (sic) of a magic formula to turn trash into liquid gold,ROFLMAO!!!!!!!

[Rawnoc] Some people are relatively easy to fool though,... so I take no pride in being a...

Rawnoc — 2/1/2016 11:00:41 AM

Some people are relatively easy to fool though,... so I take no pride in being able to do so here.

Oh the iron of that statement on the board of a biowreck scam claiming to use magic to cure any virus. ROFL!!!!!!

[NewMoney_812] "basher touts" What? ROFL! What the eff is that?

NewMoney_812 — 1/28/2016 6:43:21 PM

[NewMoney_812] I'm wounded.

NewMoney_812 — 1/28/2016 6:41:42 PM

[Rawnoc] invest07 Quits Day Job.... .....Film at 11.

Rawnoc — 1/28/2016 12:23:06 PM

[invest07] >>>>>ROFL....just took a peek at Yahoo for the first time in a while.<<<<< You ...

invest07 — 1/28/2016 10:31:20 AM

>>>>>ROFL....just took a peek at Yahoo for the first time in a while.<<<<<

You are so corrupt you can't even lie with a straight line of thought can you, ROFL?

[invest07] The only paid touts most posters agree on are you and Rawnoc who are known bashe...

invest07 — 1/28/2016 10:25:55 AM

The only paid touts most posters agree on are you and Rawnoc who are known basher touts after you pump and dump then bash after you short.

[drkaz] Really? Coulda fooled me. Some people are relatively easy to fool though,... so ...

drkaz — 1/24/2016 6:59:40 PM

Really? Coulda fooled me.

Some people are relatively easy to fool though,... so I take no pride in being able to do so here.

[NewMoney_812] "I could give a rat's hairy arse what you think or say about what I write" Rea...

NewMoney_812 — 1/24/2016 5:32:48 PM

"I could give a rat's hairy arse what you think or say about what I write"

Really? Coulda fooled me.

"none of it has had any negative impact on my investment NNVC"

Ok, that I agree with. NNVC needs no help being the most obvious really bad penny stock disaster in years. They have screwed the pooch all by themselves, and us trying to point that out will not have any effect on it.
Nor will you posting poorly written pumps on Seeking Alpha.

Nor did Pump Terminator tank the stock. All he did was point out the scheme to the world and predict, quite accurately, a potential 80% downside that came to pass thanks to the bumbling idiots at NNVC.

What I am hanging around for is the end game where we find out if they're bumbling idiot wanna be scientists who can barely make a rum and coke much less a nano machine, or are they garden variety crooks.

[Rawnoc] 500 gram batch of Flucide still not achieved. lol What a POS

Rawnoc — 1/22/2016 1:54:12 PM

[Rawnoc] ROFL....just took a peek at Yahoo for the first time in a while. harding_a1 aga...

Rawnoc — 1/22/2016 12:57:33 PM

ROFL....just took a peek at Yahoo for the first time in a while. harding_a1 again me lol. He doesn't even post like me even remotely. I see he has your panties up in a bunch though. lol lol lol lol

[Rawnoc] Yeah you don't care what I have to say except that you find it extremely importa...

Rawnoc — 1/22/2016 12:31:10 PM

Yeah you don't care what I have to say except that you find it extremely important to let me know that all the time.

ROFL!!!!

(1) Bragging about being upside-down on this POS (so can buy cheaper lol lol lol) that has severely disappointed virtually all of your timeframes -- ones that I warned you about were beyond ridiculous -- is quite priceless.

(2) I have NEVER -- repeat -- NEVER been wrong on my predictions of doom for a biowreck. NNVC won't be the first, or the last, but rather a very long history of successful predictions in this regard. To be fair, this perfect track record on biowrecks is because I select easy targets. In this case, some con artist crook in charge of telling the world through penny pump sites that he has a cure for all viruses? ROFL!!!!! How are you going to face the wife when this thing implodes and she finds out you fell for that crap?

(3) If you were stone-cold sober talking about using a P/E ratio on sales then you simply have NO idea what you are doing regarding this or any other stock.

Jim Jones had nothing on Seymour.

[drkaz] It must just eat you up inside to know that: 1) I could give a rat's hairy ar...

drkaz — 1/22/2016 12:01:40 PM

It must just eat you up inside to know that:

1) I could give a rat's hairy arse what you think or say about what I write,.... and that none of it has had any negative impact on my investment NNVC,.... and that in fact that I have continued to build my stash of NNVC shares over the last nearly 2 years you have spent bashing the company,... at a discount to my long-term cost average. Thanks for the small part that you might have played in that btw.

2) That your take on NNVC's long-term outcome will - much like just about everything else you either bash or pump - be demonstrated to be wrong,.... and I will remain unflappable.

3) I actually was stone-cold sober when I wrote that, that it is factually and logically correct, and that it could easily come to pass,.... further demonstrating that you know nothing about which you write here,... and likely elsewhere.

Later dude!

[Rawnoc] What drug were you on when you wrote this laughable nonsense? siliconinvestor.c...

Rawnoc — 1/21/2016 6:17:31 PM

What drug were you on when you wrote this laughable nonsense?

siliconinvestor.com

(1) You ASSume that every single man, woman, and child will buy the drug at full value rather than something based in reality that a relatively much smaller percentage of the people.

(2) You call an entire $45 million in mythical sales as net income -- $0 allocated for cost of the drugs or overhead which are already significant.

(3) Then you use a P/E ratio static in response to a post using P/S statics.

By the way, if you used the laughable ASSumption that everybody with a disease got cured by NNVC, there would be little if anybody left the following year to cure! The 45,000 people per year who get the disease need to get it from UNCURED people for the most part otherwise the numbers diminish to zero.

Better ASSumption, yet still wildly optimistic, would be say 25% take the drug so there are still plenty of new and uncured people to keep it spreading. Your $45 million goes down to barely any profit if any at all. It would realistically bring the company a lot closer to break-even at best which is great but it's nowhere near the laughable attempt at analysis in your post.

No wonder you're getting your butt handed to you -- Even the basic mathematics of stocks escape you.

[NewMoney_812] You know exactly who it is. And how much money has been milked out of sucker inv...

NewMoney_812 — 1/20/2016 6:56:08 AM

You know exactly who it is. And how much money has been milked out of sucker investors that have been led astray all the way down from $7 to penny land with this crap.

Shame.