Honestly, I thought it more likely than not that this week would see the pendulum swing back again, but it isn’t horrible, such that the net for the last two weeks is still a significant plus. So this week while the NASDAQ composite cooled to just a 1% gain, both the biotech indices were negative, enough to again move their YTD performances back into the red.
Probably the biggest news for biotechs this week was NVAX’s announcement Friday of a huge licensing agreement with Sanofi, with half a billion dollars in cash upfront, and an additional $700 million based on meeting a number of milestones. The agreement will include the commercialization of a combined Covide-19 and flu shot, and give Sanofi a minority holding in NVAX. This resulted in a weekly gain of +82% of its original price at the start of the contest, with almost all the activity on Friday. It also managed to put the big squeeze on what is among the most heavily shorted stocks in the US.
DSGN gained +32% for the week in response to their first quarter financials and releasing a discussion of upcoming expectations. PSTV was up +21% after announcing a private placement of up to $18 million. ZLAB added +14% with the release of first quarter financials, and the Aussies of CU6.AX gained another +12.5% for the week, adding to last week’s gains to put them in fifth place for their YTD performance of +99%.
This week’s big loser was GLYC (-66%) after announcing a failed Phase III trial, making it the worst holding YTD as well, -89%. VERU (-42%) and JSPR (-40%) gave back almost all of their gains of the previous week, dropping VERU from the top five YTD performers. IOVA’s first quarter earnings beat expectations, though the report’s lagging sales numbers may have resulted in the -33% drop. ENTA’s earnings report also disappointed to the tune of a -27% loss for the week.
Overall the contest portfolios shed -$4.6k on average, but the average YTD return is still in the black (+$7.9k), just under the NASDAQ composite's YTD return of +$8.9k.
Only three portfolios managed a positive return for the week, though YTD ten contestants ae still in the black. TOMATO had the best return, +$5.4k, as the only portfolio with a position in NVAX. This brought TOMATO up two spots in the YTD rankings to eighth place (+$7.6k). Likewise, STEVE LOKNESS was in second for the week (+$1.9k), the sole holder of DSGN.
Besides TOMATO every other of the top eight YTD contestants were in the red for the week, so changes in the rankings were more a matter of who had a less bad week. BLADERUNNER had the worst week, (-$22k), with holdings in GLYC, JSPR, and IOVA, but stayed in the number two spot YTD, even though the gap between them and number one BULBAMAN increased to $30k. RAJU_BIJLEE, another holder of both GLYC and IOVA, dropped from third to fourth, changing places with ERIKOTTO.
Report Time Ranges
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| 5/3/24
| 5/10/24
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| YTD
| 12/31/2023
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| Index Portfolios’ Performance
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| Symbol
| Recent P/L
| Recent %
| YTD P/L
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| ^IXIC
| $1,229.34
| 1.1%
| $8,856.73
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| ^NBI
| -$1,137.24
| -1.1%
| -$964.31
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| ^SPSIBI
| -$2,284.66
| -2.3%
| -$1,314.37
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| Share Performance
| Recent Performance
| YTD Performance
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| Top Five
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| Bottom Five
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| Top Five
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| Bottom 5
| Symbol
| P/L / Initial Price
| Symbol
| P/L / Initial Price
| Symbol
| YTD P/L / Initial Price
| Symbol
| YTD P/L/ Initial Price
| NVAX
| 82.3%
| GLYC
| -66.2%
| VKTX
| 295.7%
| GLYC
| -88.7%
| DSGN
| 32.1%
| VERU
| -41.7%
| JSPR
| 170.3%
| AMLX
| -88.1%
| PSTV
| 20.6%
| JSPR
| -40.4%
| PYXS
| 141.1%
| CNSP
| -84.6%
| ZLAB
| 14.0%
| IOVA
| -32.8%
| CRDF
| 129.1%
| PACB
| -82.0%
| CU6.AX
| 12.5%
| ENTA
| -26.8%
| CU6.AX
| 99.0%
| EYEN
| -62.9%
| Average and Median Portfolio Performance
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| Recent P/L
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| YTD P/L
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| Avg.
| Median
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| Avg
| Median
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| -$4,612.99
| -$1,953.47
| DART LANZER
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| $7,899.15
| $5,715.09
| JACK HARTMANN
| Top Seven Portfolio Performances
| Top Recent Performers
| Top YTD Performers
| Contestant (Prev. Rank)
| Recent P/L
| P/L vs. ^SPSIBI
| YTD P/L (Rank)
| Contestant (Prev. Rank)
| YTD P/L
| vs. Top Portfolio
| P/L vs. ^SPSIBI
| Rec. P/L (Rank)
| 1 - TOMATO (10)
| $5,389.00
| $7,673.66
| $7,643.44 (8)
| 1 - BULBAMAN (1)
| $73,590.79
| ——
| $74,905.16
| -$2,002.07 (10)
| 2 - STEVE LOKNESS (11)
| $1,873.13
| $4,157.79
| -$767.12 (11)
| 2 - BLADERUNNER (2)
| $43,898.33
| $29,692.46
| $45,212.70
| -$22,068.04 (17)
| 3 - ALONER (17)
| $80.02
| $2,364.68
| -$8,675.32 (14)
| 3 - ERIKOTTO (4)
| $22,149.45
| $51,441.34
| $23,463.83
| -$7,559.00 (13)
| 4 - TRACE I11 (13)
| -$72.62
| $2,212.04
| $10,860.45 (6)
| 4 - RAJU_BIJLEE (3)
| $17,520.13
| $56,070.66
| $18,834.50
| -$15,718.03 (16)
| 5 - JACK HARTMANN (8)
| -$688.90
| $1,595.76
| $5,715.09 (9)
| 5 - TECHNETIUM (6)
| $12,376.71
| $61,214.08
| $13,691.08
| -$6,358.56 (12)
| 6 - KATHLEEN (4)
| -$1,081.68
| $1,202.98
| $1,997.82 (10)
| 6 - TRACE I11 (7)
| $10,860.45
| $62,730.33
| $12,174.83
| -$72.62 (4)
| 7 - A. J. MULLEN (14)
| -$1,217.63
| $1,067.03
| -$23,612.00 (17)
| 7 - DEW_DILIGENCE (5)
| $9,214.71
| $64,376.08
| $10,529.09
| -$12,453.22 (15)
| 8 - NOTABOT (15)
| -$1,901.80
| $382.86
| -$8,671.88 (13)
| 8 - TOMATO (10)
| $7,643.44
| $65,947.35
| $8,957.81
| $5,389.00 (1)
| Top Portfolios’ Contents
| Top Recent Performance Portfolio (TOMATO)
| Top YTD Performance Portfolio (BULBAMAN)
| Symbol (Rank)
| Initial Allocation
| Value/Total | ROI
| YTD Stock P/L
| Recent Stock P/L
| % Current Price Change for $1,000 P/L
| Symbol (Rank)
| Initial Allocation
| Value/Total | ROI
| YTD Stock P/L
| Recent Stock P/L
| % Current Price Change for $1,000 P/L
| BTAI
| 10.00%
| 6.6% | -29.2%
| -$2,915.25
| -$1,627.12
| 14.1%
| CU6.AX
| 20.00%
| 22.9% | 99.0%
| $19,800.07
| $2,502.02
| 2.5%
| CCCC
| 10.00%
| 10.1% | 9.0%
| $902.65
| -$1,026.55
| 9.2%
| CYTH
| 10.00%
| 5.3% | -7.5%
| -$754.72
| -$251.57
| 10.8%
| HROW
| 20.00%
| 19.2% | 3.6%
| $714.29
| $2,178.57
| 4.8%
| LRMR
| 10.00%
| 9.0% | 56.5%
| $5,648.35
| -$1,417.58
| 6.4%
| NVAX
| 10.00%
| 17.2% | 85.0%
| $8,500.00
| $8,229.17
| 5.4%
| PMN
| 10.00%
| 9.5% | 64.3%
| $6,434.78
| -$608.70
| 6.1%
| NVCT
| 10.00%
| 7.1% | -23.3%
| -$2,326.14
| -$2,086.33
| 13.0%
| SNGX
| 10.00%
| 3.0% | -47.5%
| -$4,751.32
| -$73.68
| 19.1%
| OCUL
| 10.00%
| 11.8% | 26.9%
| $2,690.58
| -$1,143.50
| 7.9%
| TCON
| 10.00%
| 3.2% | -44.9%
| -$4,488.86
| $199.89
| 18.1%
| TARA
| 10.00%
| 14.9% | 60.0%
| $5,999.15
| $479.97
| 6.3%
| TLX.AX
| 15.00%
| 12.9% | 49.0%
| $7,347.30
| $331.59
| 4.5%
| TCON
| 10.00%
| 5.1% | -44.9%
| -$4,488.86
| $199.89
| 18.1%
| VKTX
| 15.00%
| 34.2% | 295.7%
| $44,355.19
| -$2,684.04
| 1.7%
| TERN
| 10.00%
| 8.0% | -14.3%
| -$1,432.97
| $184.90
| 11.7%
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