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Biotech / Medical : Immunomedics (IMMU) - moderated -- Ignore unavailable to you. Want to Upgrade?


To: dorightbythem who wrote (45925)4/27/2018 12:15:43 PM
From: Fitzhughlaw12 Recommendations

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I got a bootleg copy from another source. What intrigued me about the event is that in addition to Doctor Vahdat, who was one of the panelists at the December event after the SABCS, Dr. Tagawa will be participating, and he was previously featured in the January of 2017 release that updated SG as follows:

"In addition to TNBC, Immunomedics is making progress with IMMU-132 across the other three advanced indications. In patients with urothelial cancer, especially metastatic urinary bladder cancer, Dr. Scott T. Tagawa, Associate Professor of Medicine and Urology, Weill Cornell Medical College, and Attending Physician, New York-Presbyterian Hospital, New York, reported on 27 assessable patients from more than 40 patients enrolled. The objective response rate was 33%, including one complete and eight partial remissions. The duration of objective response was a median of 7.5 months, with one patient with a partial response approaching 17 months. The clinical benefit rate at six months or later was 59%, but 10 patients are still under therapy. Overall, 70% of the patients showed tumor shrinkage from baseline with IMMU-132 therapy. The median PFS and OS on an ITT basis were seven and almost 16 months, respectively. The safety profile was similar to the findings in patients with TNBC.

“These patients had a median of two prior therapies and had extensive metastatic disease. While patients with metastatic urothelial cancer respond well to initial therapy with a platinum-containing regimen, few options are available after they become refractive. The recent approval of an immune checkpoint inhibitor has been an important advance, but only a fraction of patients respond. In our trial, we had two such patients who were unresponsive to this therapy but showed tumor shrinkage with IMMU-132,” Dr. Tagawa said: “I am impressed with the results we have seen in this difficult-to-treat population and we continue to enroll these advanced patients in order to better position this new agent in the management of this disease, either as a second line therapy or perhaps someday in combination with chemotherapy or an immune checkpoint inhibitor.” Source: sec.gov

Also, another shareholder sent me this earlier today - Dr. Tagawa's remarks in February of 2017, and thus although dated and only about 90 seconds, is worth a look: https://www.youtube.com/watch?v=Jw72tz5tRek. Also, here's one from 2016, and it's interesting to see his initial thoughts on SG's potential: youtube.com

Thus, because of his presence at this impending event and ongoing involvement with SG in UTC, I'm inferring that the investor event won't be limited to breast cancers, but will include an update on urothelial.