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From: Sam6/21/2017 11:00:21 PM
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25 Hilariously Unfortunate Things Moms Have Done While Sleep-Deprived

Being a parent is a beautiful thing. but it also involves countless sleepless nights. Let's face it - you're not getting much sleep the first few years. If you need more proof, check out these 25 hilarious confessions from real, sleep-deprived moms.

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From: Sam6/25/2017 9:09:57 PM
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In 10 Years, Your iPhone Won't Be a Phone Anymore
DOW JONES & COMPANY, INC. 9:14 AM ET 6/25/2017

It's 2027, and you're walking down the street, confident you'll arrive at your destination even though you don't know where it is. You may not even remember why your device is telling you to go there.

There's a voice in your ear giving you turn-by-turn directions and, in between, prepping you for this meeting. Oh, right, you're supposed to be interviewing a dog whisperer for your pet-psychiatry business. You arrive at the coffee shop, look around quizzically, and a woman you don't recognize approaches. A display only you can see highlights her face and prints her name next to it in crisp block lettering, Terminator-style. Afterward, you'll get an automatically generated transcript of everything the two of you said.

As the iPhone this week marks the 10th anniversary of its first sale, it remains one of the most successful consumer products in history. But by the time it celebrates its 20th anniversary, the "phone" concept will be entirely uprooted: That dog-whisperer scenario will be brought to you even if you don't have an iPhone in your pocket.

Sure, Apple(AAPL) may still sell a glossy rectangle. (At that point, iPhones may also be thin and foldable, or roll up into scrolls like ancient papyri.) But the suite of apps and services that is today centered around the physical iPhone will have migrated to other, more convenient and equally capable devices -- a "body area network" of computers, batteries and sensors residing on our wrists, in our ears, on our faces and who knows where else. We'll find ourselves leaving the iPhone behind more and more often.

Trying to predict where technology will be in a decade may be a fool's errand, but how often do we get to tie up so many emerging trends in a neat package?

Apple (AAPL) is busy putting ever more powerful microprocessors, and more wireless radios, in every one of its devices. Siri is getting smarter and popping up in more places. Meanwhile Apple(AAPL) is going deep on augmented reality, giving developers the ability to create apps in which our physical world is filled with everything from Pokémon to whatever IKEA furniture we want to try in our living rooms. All these technologies -- interfacing with our smart homes, smart cars, even smart cities -- will constitute not just a new way to interact with computers but a new way of life. And of course, worrisome levels of privacy invasion.

Apple's (AAPL) acquisitions -- it buys a company every three to four weeks, Chief Executive Tim Cook has said -- tend to be highly predictive of its future moves. Since it first bought Siri in 2010, Apple(AAPL) has continued to make acquisitions in artificial intelligence -- Lattice Data, Turi and Perceptio among them, all of which specialize in some form of machine learning. The company is reportedly working on its own chips for AI.

Apple's (AAPL) preview of iOS 11, with deeper integration of Siri than ever, suggests it hopes to make Siri capable of doing nearly everything on an iPhone that we currently do through its touch interface.

Apple (AAPL) has also made many acquisitions related to augmented reality -- the overlay of computer interfaces and three- dimensional objects on a person's view of the real world -- including Primesense and Metaio. Mr. Cook has said he is so excited about AR he wants to " yell out and scream."

By 2027, the problem of bulky AR headsets like Microsoft's HoloLens should be solved, which means Apple(AAPL) and others are likely to release some sort of smart eyeglasses. With their ability to convincingly supplement our visual and auditory reality, delivering information at the time and place most appropriate, they'll occasion a cultural change as big as the introduction of the smartphone itself.

"What you're going to see with all this augmentation is the psychology of using your phone could change dramatically," says Ryan Walsh, a partner at venture-capital firm Floodgate who from 2014 to 2016 directed product management for media at Apple(AAPL). "Instead of using your phone to get away from the world, you'll use it to join in the world in a much deeper and more meaningful way," he says.

Augmented reality and artificial intelligence will also benefit from the Internet of Things trend: everyday gadgets getting sensors, actuators and a wireless internet connection. Apple(AAPL) controls smart-home products with HomeKit. It aggregates health information with HealthKit, and ties in the car (CarPlay), cash register (Apple Pay) and even the StairMaster (GymKit). Apple(AAPL) clearly wants its devices to connect to everything on Earth.

With our every action mapped to every outdoor and indoor space we inhabit -- combined with the predictive power of AI and distributed across a suite of devices for which Siri has become the default interface -- the result could be a life directed by our gadgets, a sort of "Choose Your Own Adventure" for our daily routines.

At first, this will be straightforward. Having automatically filled our calendars using the kind of scheduling AI that already exists, our devices will direct us from one task to another, even suggesting transportation -- ridesharing, mass transit or flying car. But the relationship will change as the AI gets to know more about you.

"You might be walking by someplace and it might tell you, 'Hey, you should go in here, they make a great cup of coffee and there's also this person you really would like, too'," says Jonathan Badeen, co-founder and chief strategy officer of dating app Tinder, where he leads teams that think about how to incorporate Apple's(AAPL) latest technology into apps.

By 2027, Apple(AAPL) and its competitors will also have cemented a world of tradeoffs: If you want your life enhanced by AI and all the rest of this tech, you're going to have to submit to constant surveillance -- by your devices or, in many cases, by the tech giants themselves. Apple's(AAPL) bet is that you will trust it to do this: The company's privacy stance is that it isn't going to look at or share your data, and it will be encrypted so others can't look at it, either.

Getting used to that won't be easy. Just as getting in a stranger's car or sleeping in a stranger's home seemed crazy before Uber and Airbnb, the 2027 iPhone's most important differentiator may be our willingness to accept things we can't even fathom today.

  (END) Dow Jones Newswires 

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From: Sam6/28/2017 8:58:44 AM
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“An AI algorithm makes the perfect chess move while the room is on fire,” she said, repeating a joke coined by another researcher about the lack of contextual awareness in deep learning.

Expert Panel Debunks AI Hype
Neural networks seen as huge but limited

Rick Merritt
6/26/2017 11:51 AM EDT

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From: Sam6/28/2017 2:00:31 PM
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How An Entire Nation Became Russia's Test Lab for Cyberwar
Andy Greenberg
June 20, 2017

In 2009, when the NSA’s Stuxnet malware silently accelerated a few hundred Iranian nuclear centrifuges until they destroyed themselves, it seemed to offer a preview of this new era. “This has a whiff of August 1945,” Michael Hayden, former director of the NSA and the CIA, said in a speech. “Somebody just used a new weapon, and this weapon will not be put back in the box.”

Now, in Ukraine, the quintessential cyberwar scenario has come to life. Twice. On separate occasions, invisible saboteurs have turned off the electricity to hundreds of thousands of people. Each blackout lasted a matter of hours, only as long as it took for scrambling engineers to manually switch the power on again. But as proofs of concept, the attacks set a new precedent: In Russia’s shadow, the decades-old nightmare of hackers stopping the gears of modern society has become a reality.

And the blackouts weren’t just isolated attacks. They were part of a digital blitzkrieg that has pummeled Ukraine for the past three years—a sustained cyber­assault unlike any the world has ever seen. A hacker army has systematically undermined practically every sector of Ukraine: media, finance, transportation, military, politics, energy. Wave after wave of intrusions have deleted data, destroyed computers, and in some cases paralyzed organizations’ most basic functions. “You can’t really find a space in Ukraine where there hasn’t been an attack,” says Kenneth Geers, a NATO ambassador who focuses on cybersecurity.

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From: Sam7/8/2017 11:28:48 AM
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Four myths about slavery in the US
The Conversation
21 Oct 2014 at 07:30 ET

People think they know everything about slavery in the United States, but they don’t. They think the majority of African slaves came to the American colonies, but they didn’t. They talk about 400 hundred years of slavery, but it wasn’t. They claim all Southerners owned slaves, but they didn’t. Some argue it was a long time ago, but it wasn’t.

Slavery has been in the news a lot lately. Perhaps it’s because of the increase in human trafficking on American soil or the headlines about income inequality, the mass incarceration of African Americans or discussions about reparations to the descendants of slaves. Several publications have fueled these conversations: Ta-Nehisi Coates’ The Case for Reparations in The Atlantic Monthly, French economist Thomas Picketty’s Capital in the Twenty First Century, historian Edward Baptist’s The Half Has Never Been Told: Slavery and The Making of American Capitalism, and law professor Bryan A. Stevenson’s Just Mercy: A Story of Justice and Redemption.

As a scholar of slavery at the University of Texas at Austin, I welcome the public debates and connections the American people are making with history. However, there are still many misconceptions about slavery.

I’ve spent my career dispelling myths about “the peculiar institution.” The goal in my courses is not to victimize one group and celebrate another. Instead, we trace the history of slavery in all its forms to make sense of the origins of wealth inequality and the roots of discrimination today. The history of slavery provides deep context to contemporary conversations and counters the distorted facts, internet hoaxes and poor scholarship I caution my students against.

Four myths about slavery

Myth One: The majority of African captives came to what became the United States.

Truth: Only 380,000 or 4-6% came to the United States. The majority of enslaved Africans went to Brazil, followed by the Caribbean. A significant number of enslaved Africans arrived in the American colonies by way of the Caribbean where they were “seasoned” and mentored into slave life. They spent months or years recovering from the harsh realities of the Middle Passage. Once they were forcibly accustomed to slave labor, many were then brought to plantations on American soil.

Myth Two: Slavery lasted for 400 years.

Popular culture is rich with references to 400 years of oppression. There seems to be confusion between the Transatlantic Slave Trade (1440-1888) and the institution of slavery, confusion only reinforced by the Bible, Genesis 15:13:

Then the Lord said to him, ‘Know for certain that for four hundred years your descendants will be strangers in a country not their own and that they will be enslaved and mistreated there.’

Listen to Lupe Fiasco – just one Hip Hop artist to refer to the 400 years – in his 2011 imagining of America without slavery, “All Black Everything”:

You would never know
If you could ever be
If you never try
You would never see
Stayed in Africa
We ain’t never leave
So there were no slaves in our history
Were no slave ships, were no misery, call me crazy, or isn’t he
See I fell asleep and I had a dream, it was all black everything

[Verse 1]
Uh, and we ain’t get exploited
White man ain’t feared so he did not destroy it
We ain’t work for free, see they had to employ it
Built it up together so we equally appointed
First 400 years, see we actually enjoyed it

A plantation owner with his slaves.

National Media Museum from UK

Truth: Slavery was not unique to the United States; it is a part of almost every nation’s history from Greek and Roman civilizations to contemporary forms of human trafficking. The American part of the story lasted fewer than 400 years.

How do we calculate it? Most historians use 1619 as a starting point: 20 Africans referred to as ”servants” arrived in Jamestown, VA on a Dutch ship. It’s important to note, however, that they were not the first Africans on American soil. Africans first arrived in America in the late 16th century not as slaves but as explorers together with Spanish and Portuguese explorers. One of the best known of these African “conquistadors” was Estevancio who traveled throughout the southeast from present day Florida to Texas. As far as the institution of chattel slavery – the treatment of slaves as property – in the United States, if we use 1619 as the beginning and the 1865 Thirteenth Amendment as its end then it lasted 246 years, not 400.

Myth Three: All Southerners owned slaves.

Truth: Roughly 25% of all southerners owned slaves. The fact that one quarter of the Southern population were slaveholders is still shocking to many. This truth brings historical insight to modern conversations about the Occupy Movement, its challenge to the inequality gap and its slogan “we are the 99%.”

Take the case of Texas. When it established statehood, the Lone Star State had a shorter period of Anglo-American chattel slavery than other Southern states – only 1845 to 1865 – because Spain and Mexico had occupied the region for almost one half of the 19th century with policies that either abolished or limited slavery. Still, the number of people impacted by wealth and income inequality is staggering. By 1860, the Texas enslaved population was 182,566, but slaveholders represented 27% of the population, controlled 68% of the government positions and 73% of the wealth. Shocking figures but today’s income gap in Texas is arguably more stark with 10% of tax filers taking home 50% of the income.

Myth Four: Slavery was a long time ago.

Truth: African-Americans have been free in this country for less time than they were enslaved. Do the math: Blacks have been free for 149 years which means that most Americans are two to three generations removed from slavery. However, former slaveholding families have built their legacies on the institution and generated wealth that African-Americans have not been privy to because enslaved labor was forced; segregation maintained wealth disparities; and overt and covert discrimination limited African-American recovery efforts.

The value of slaves Economists and historians have examined detailed aspects of the enslaved experience for as long as slavery existed. Recent publications related to slavery and capitalism explore economic aspects of cotton production and offer commentary on the amount of wealth generated from enslaved labor.

My own work enters this conversation looking at the value of individual slaves and the ways enslaved people responded to being treated as a commodity. They were bought and sold just like we sell cars and cattle today. They were gifted, deeded and mortgaged the same way we sell houses today. They were itemized and insured the same way we manage our assets and protect our valuables.

Extensive Sale of Choice Slaves, New Orleans 1859, Girardey, C.E.

Natchez Trace Collection, Broadside Collection, Dolph Briscoe Center for American History

Enslaved people were valued at every stage of their lives, from before birth until after death. Slaveholders examined women for their fertility and projected the value of their “future increase.” As they grew up, enslavers assessed their value through a rating system that quantified their work. An “A1 Prime hand” represented one term used for a “first rate” slave who could do the most work in a given day. Their values decreased on a quarter scale from three-fourths hands to one-fourth hands, to a rate of zero, which was typically reserved for elderly or differently abled bondpeople (another term for slaves.)

Guy and Andrew, two prime males sold at the largest auction in US History in 1859, commanded different prices. Although similar in “all marketable points in size, age, and skill,” Guy commanded $1240 while Andrew sold for $1040 because “he had lost his right eye.” A reporter from the New York Tribune noted “that the market value of the right eye in the Southern country is $240.” Enslaved bodies were reduced to monetary values assessed from year to year and sometimes from month to month for their entire lifespan and beyond. By today’s standards, Andrew and Guy would be worth about $33,000-$40,000.

Slavery was an extremely diverse economic institution; one that extrapolated unpaid labor out of people in a variety of settings from small single crop farms and plantations to urban universities. This diversity is also reflected in their prices. Enslaved people understood they were treated as commodities.

“I was sold away from mammy at three years old,” recalled Harriett Hill of Georgia. “I remembers it! It lack selling a calf from the cow,” she shared in a 1930s interview with the Works Progress Administration. “We are human beings” she told her interviewer. Those in bondage understood their status. Even though Harriet Hill “was too little to remember her price when she was three, she recalled being sold for $1400 at age 9 or 10, “I never could forget it.”

Slavery in popular culture Slavery is part and parcel of American popular culture but for more than 30 years the television mini-series Roots was the primary visual representation of the institution except for a handful of independent (and not widely known) films such as Haile Gerima’s Sankofa or the Brazilian Quilombo. Today Steve McQueen’s 12 Years a Slave is a box office success, actress Azia Mira Dungey has a popular web series called Ask a Slave, and in Cash Crop sculptor Stephen Hayes compares the slave ships of the 18th century with third world sweatshops.

From the serious – PBS’s award-winning Many Rivers to Cross – and the interactive Slave Dwelling Project- whereby school aged children spend the night in slave cabins – to the comic at Saturday Night Live, slavery is today front and center.

The elephant that sits at the center of our history is coming into focus. American slavery happened — we are still living with its consequences.

By Daina Ramey Berry, University of Texas

Daina Ramey Berry receives funding from the National Endowment for the Humanities and is a Public Voices Fellow with The Op-Ed Project.

This article was originally published on The Conversation.
Read the original article.

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From: Sam7/9/2017 9:09:29 AM
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Biographical video of Steve Jobs, Apple, starting a business, and life.

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From: Sam7/12/2017 8:33:10 PM
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FDA cancer advisers OK ‘major advance’ — individualized cancer therapy
Health Care 07/12/2017, 05:21pm

A panel of cancer experts recommended approval Wednesday of an experimental therapy for treating children and young adults with advanced leukemia that could be the first gene therapy approved in the United States, potentially opening the door to a wave of treatments custom-made to target a patient’s cancer.

The advisory panel to the federal Food and Drug Administration advisory panel voted 10-0 in favor of the treatment developed by the University of Pennsylvania and Novartis Corp. The FDA usually follows recommendations of its expert panels.

The therapy could be the first of a wave of individualized treatments custom-made to target a patient’s cancer.

“This is a major advance,” said panel member Dr. Malcolm A. Smith of the National Cancer Institute.

Smith said the treatment is “ushering in a new era.”

Called CAR-T, it involves removing immune cells from a patient’s blood, genetically altering them — in effect, reprogramming them to create an army of cells that can zero in on and destroy cancer cells — and then injecting them back into the patient to fight these blood cancers.

The unanimous vote came after lengthy discussion and impassioned pleas from the fathers of two young patients whose lives were saved by the therapy. The one-time leukemia treatment would be for children and young adults with the most common form of childhood cancer, known as ALL.

“Our daughter was going to die, and now she leads a normal life,” said Tom Whitehead of Philipsburg, Pennsylvania.

Five years ago, Emily Whitehead, now 12, was the first child to receive the experimental therapy.

“We believe when this treatment is approved, it will save thousands of children’s lives around the world,” Whitehead said.

After decades of setbacks and disappointments in efforts to fix, replace, or change genes to cure diseases, several companies are near the finish line in a race to bring CAR-T and other types of gene therapy to patients. Kite Pharma also has a CAR-T therapy in FDA review and Juno Therapeutics, and others are in late stages of testing.

Human T cells belonging to cancer patients arrive at Novartis Pharmaceuticals Corp.’s Morris Plains, N.J., facility. This laboratory is where the T cells of cancer patients are processed and turned into super cells as part of a new gene therapy-based cancer treatment. | Novartis Pharmaceuticals Corp. via AP

Novartis is seeking approval to use the treatment for patients aged 3 to 25 with a blood cancer called acute lymphoblastic leukemia whose disease has spread or failed to respond to standard treatment. That happens to more than 600 patients in the U.S. each year. At that point, they have limited options — all more toxic than the CAR-T therapy — and survival chances are slim. ALL accounts for a quarter of all cancers in children under age 15.

In a key test, results were far better than chemotherapy and even newer types of cancer drugs. Of the 52 patients whose results were analyzed, 83 percent had complete remission, meaning their cancer vanished. Most patients suffered serious side effects, but nearly all recovered.

CAR-T therapy starts with filtering key immune cells called T cells from a patient’s blood. In a lab, a gene is then inserted into the T cells that prompts them to grow a receptor that targets a special marker found on some blood cancers. Millions of copies of the new T cells are grown in the lab, then injected into the patient’s bloodstream where they can seek out and destroy cancer cells. Doctors call it a “living drug” — permanently altered cells that continue to multiply in the body into an army to fight the disease.

During the patient testing, the whole process took about 16 weeks, which can be too long a wait for some desperately ill patients, the FDA advisers noted during the meeting in Silver Spring, Maryland. Drug company officials said they can now produce a treatment and get it to a patient in about three weeks.

Novartis said in a statement that it has long believed CAR-T therapy could “change the cancer-treatment paradigm.”

The cost of CAR-T therapy is likely to be hundreds of thousands of dollars, but it’s only given once. Typically, cancer patients take one or more drugs until they stop working, then switch to other drugs, so treatment — and side effects — can go on for years.

The treatment’s short-term side effects, including fever and hallucinations, are often intense as the body’s revved up immune system goes on the attack. The long-term side effects of the treatment are unknown. It’s also unclear if patients whose cancer goes into remission will be cured or will have their cancer return eventually. The FDA panel recommended that patients who get the treatment be monitored for 15 years.

Other biotech and pharmaceutical companies are developing types of gene therapy to treat solid cancers and rare gene-linked diseases. A few products have been approved elsewhere — one for head and neck cancer in China in 2004 and two in Europe, most recently GlaxoSmithKline’s Strimvelis. That was approved last year for a deadly condition called severe combined immunodeficiency and launched with a $670,000 price tag.

UniQure’s Glybera was approved for a rare enzyme disorder. It was used only once in five years, likely due to its $1 million-plus price tag, so uniQure is pulling it from the market.

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From: Sam7/12/2017 10:50:27 PM
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Why Do Geese Fly in V Formations?


It’s an iconic image of fall—a V of geese high overhead, migrating south for the winter. Several other bird species, such as flamingos, also fly in V formations, but geese are the most well known. On any given fall day, numerous Vs can be seen passing gracefully below the clouds. Most birds actually don’t migrate in the V formation; smaller birds tend to fly in huge amorphous flocks. Others fly in a simple line. But why do geese and other birds fly in V formations?

Writing in the journal “Auk,” John Badgerow examined numerous formations of geese, hoping to come up with a definitive answer. Aerodynamism was not initially seen as a primary reason for the behavior; previous analyses had suggested that the birds were too far apart to benefit from the energy saved. Instead, the angle of the V suggested that the primary purpose was a form of visual communication—the geese that composed both diagonal lines, each slightly angled from one another, would have an unobstructed view of the lead goose who determined the flight path of the flock.

Badgerow, unconvinced, decided to test both hypotheses. Working from film, he analyzed the geometry of the formations. Badgerow calculated that maximum energetic advantage (compared to solo flight) is achieved at exactly 0.16 meters between the wingtips of a bird and the one following. The spacing requirements explain why only certain birds fly in V-formations—only birds with large wingspans and slow beats can achieve the energy saving. Rapid or erratic flapping creates too much wake turbulence, which disrupts the formation. Migrating geese effectively function like airplanes.

At the same time, information about changes in course and velocity must be communicated to other members of the flock, so visual communication does play a role. The angle seems to be chosen so all members of a flock can see the leader and adjust to any changes. Flocks contain both experienced and new migrants, so communicating information about rest and feeding areas is vital.

In practice, turbulence, air currents, and other factors make it extremely difficult for the geese to maintain the exact spacing needed to maximize efficiency or communication, and actual efficiency improvements are only about 20% of the theoretical maximum. Geese go to great lengths to maintain their formation as best as possible, so Badgerow suggests that while both communication and efficiency play a role in V-formations, energy efficiency is the primary motivator. More recent studies have confirmed that flying in the lead is the most tiring position, so geese take turns at the head of the V in order to allow leaders to rest.


JSTOR Citations An Analysis of Function in the Formation Flight of Canada Geese By: John P. Badgerow

The Auk, Vol. 105, No. 4 (Oct., 1988), pp. 749-755

American Ornithologists' Union

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From: Sam7/13/2017 8:28:27 AM
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Millennials Are Attending Events in Droves Because of Fear of Missing Out

Jaimie Seaton, Skift
- Jul 12, 2017 10:00 am


“The biggest buzzword right now is FOMO [fear of missing out], and that’s a huge factor for Millennials,” said Aubri Nowowiejski, 28, an executive producer at Coterie Spark, a global meeting and corporate event-planning firm based in Houston, Texas.

“It’s all about projecting to your social media network, and painting a picture of a phenomenal lifestyle. They chase experiences over things to get those likes and comments and interactions, and that dopamine fix,” said Nowowiejski, who founded the Student Event Planners Association in 2009 while a student at Texas State University. It currently has more than 2,000 members nationwide.

In fact, the study found that nearly half of Millennials surveyed attend live events so they have something to share online; and 78 percent reported enjoying seeing other people’s experiences on social media.

The Millennial obsession with FOMO and cultivating the perfect social media feed can be a boon to consumer-focused marketing events, especially if they are free, but it also presents challenges to conference and meetings organizers who value engagement. In an effort to lure the young demographic, organizers may reach for the unique “wow” factor, and wind up with an event that is more style than substance.

“That’s one of my biggest frustrations: I want us to put down our phones,” said Nowowiejski. “We’re experiencing the whole world through a lens and we’re not present in the moment, and it is an issue. Conference planners are trying to integrate social media and meet Millennials where they are. You go to a conference and are told to live-tweet, but if I’m tweeting, am I really absorbing what the speaker is saying? It’s a double-edged sword. What did you really experience if you didn’t put your phone down?”

more at the link

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From: Sam7/15/2017 6:31:01 PM
   of 463
The Lawyer, the Addict
A high-powered Silicon Valley attorney dies. His ex-wife
investigates, and finds a web of drug abuse in his profession.

JULY 15, 2017

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