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   Biotech / MedicalBiotech for less than cash value


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From: scaram(o)uche4/3/2024 2:25:58 PM
   of 684
 
We usually look for negative EVs after a prolonged sector drought. But we've had good sector performance since November, with exception of a recent rough spot.

Matt Gamber at Twitter has looked for negative EVs under these circumstances.....

twitter.com

(thread)

Of those issues he mentions, I took a position in CMRX. Yeah, the same CMRX that brought such CMV-related misery to investors.

ONC201 for recurrent H3 K27M-mutant high-grade glioma, a molecule derived from the Oncoceutics munch. Observed toxicity in trials to date, but nothing that has derailed it.

https://aacrjournals.org/cancerdiscovery/article/13/11/2370/729854/Clinical-Efficacy-of-ONC201-in-H3K27M-Mutant

This position was taken without knowledge of market size, the difficulty penetrating it, or competitors addressing it.

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To: scaram(o)uche who wrote (682)4/3/2024 2:34:30 PM
From: scaram(o)uche
   of 684
 
Market size addressed here, also from Matt.....

mattbiotech.substack.com

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From: JamesK4/7/2025 5:49:19 PM
   of 684
 
EDIT is certainly below cash value. Feels like the worst biotech bear ever. Almost all down since 2021. Did start to do better in the fall. Then the election happened.

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