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   Biotech / MedicalGMED - GenoMed Inc.


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From: jmhollen11/14/2005 2:02:26 PM
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"Cytokine Storm" Paper Confirms GenoMed's Approach to Avian Flu

Contact: David W. Moskowitz MD CEO, GenoMed tel. 314.983.9933 dwmoskowitz@genomed.com


ST. LOUIS—November 14, 2005--GenoMed (OTC Pink Sheets GMED), a Next Generation Disease Management company whose business is public health, announced today that its approach to avian influenza was confirmed last week by a Hong Kong research group who found that the avian influenza virus induces a "cytokine storm" in human lung cells grown in tissue culture.

Dr. J.S.M. Peiris and colleagues published last week in Respiratory Research that avian influenza (H5N1) viruses isolated from dead patients cause lung cells to produce many more pro-inflammatory molecules, called "cytokines," than regular influenza A viral strains. This research confirms GenoMed's hypothesis that the host's immune response to the virus is what causes death, not the replication of the virus itself.

About GenoMed

GenoMed's broad-spectrum anti-viral approach is specifically mentioned in BioShield II, (see Section 2151 of Senate bill S. 975). GenoMed uses already existing, safe medication present in every drug store and hospital in the world. GenoMed is now charging a one-time license fee of US $10 to access its treatment approach, which is patent-pending globally. Please see www.genomed.com for details.

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From: jmhollen11/28/2005 7:40:19 PM
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GenoMed Considers Offering Low-Cost Health Insurance to America's Uninsured

Contact: David Moskowitz MD CEO, GenoMed, Inc. Tel. 314-983-9933 dwmoskowitz@genomed.com


ST. LOUIS, November 28, 2005 -- GenoMed, Inc. (Pink Sheets GMED) a Next Generation Disease Management company, announced today that it is considering partnering to offer a low-cost health insurance product to compete for the uninsured market.

By avoiding expensive hospitalizations for diabetes, high blood pressure, and emphysema, GenoMed can already slash healthcare costs for cardiovascular disease. Two-thirds of Americans die from cardiovascular disease, and one third from cancer. With its Healthchip® to serve as an early warning system for the top six common cancers in whites, breast, colon, lung, ovarian, pancreatic, and prostate, GenoMed has taken the first step towards curing cancer.

The company wants to pass these savings on to the consumer in the form of markedly lower premiums. Currently, health insurance costs $6,000 a year, but life expectancy from cardiovascular disease and cancer is still poor. GenoMed thinks it can provide better patient outcomes for up to 40% less. The company is currently looking for two other partners to provide low cost health insurance: a mail-order pharmacy to supply drugs inexpensively, and an insurance carrier for catastrophic hospitalization.

Said Dr. David Moskowitz, GenoMed's CEO and Chief Medical Officer, "If hospitalization can be avoided for most patients by judicious use of outpatient medications and tests, then insurance rates can be lowered considerably. Hospitalization will become the exception, not the norm, and catastrophic hospitalization insurance rates should apply. This is the whole promise of medical genomics and preventive molecular medicine."

GenoMed hopes to offer an insurance product inexpensive enough to attract America's 45 million uninsured patients. Given the rising cost of healthcare, other payors should soon follow as customers, including employers, state Medicaid programs, Medicare, overseas National Health Services, etc.

About GenoMed™

GenoMed is leading the clinical revolution which knowledge of disease genes makes possible. GenoMed is currently marketing its protocols to prevent kidney failure due to high blood pressure and diabetes, and to delay the progression of emphysema. The company plans to increase the scope and predictive power of its Healthchip® by collecting patient samples from additional types of cancer, and additional ethnic groups. The company is finding that its science requires it to also discover new business models.


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To: jmhollen who wrote (289)2/9/2006 11:29:19 AM
From: Tadsamillionaire
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GenoMed's Formula for Better Healthcare at Half the Price = GenoMed + President Bush's HSAs
Wednesday February 1, 9:30 am ET

ST. LOUIS, Feb. 1 /PRNewswire-FirstCall/ -- GenoMed, Inc. (Pink Sheets: GMED - News), a Next Generation Disease Management company, announced today that it can deliver better healthcare for half the cost, if coupled with the President's health savings accounts (HSAs).

biz.yahoo.com

Thanks to President Bush's HSAs, GenoMed can now offer an insurance plan inexpensive enough to attract most of America's 46 million uninsured patients. Given the high cost of healthcare, other customers should quickly follow, including large employers, state Medicaid programs, Medicare, overseas National Health Services, etc.

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From: Tadsamillionaire2/21/2006 3:46:56 PM
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GenoMed Trial Results: HIV -- Viral Load Goes to Zero
ST. LOUIS, Feb. 21 /PRNewswire-FirstCall/ -- GenoMed (Pink Sheets: GMED), a Next Generation Disease Management company whose business is public health, announced today that its first HIV patient had his viral load fall to zero after starting GenoMed's trial.

The patient is a 54 year old African American man who was diagnosed with HIV 2 years ago. He was being treated with a standard triple-drug 'cocktail' and had a stable viral load when he began GenoMed's trial this past summer, as shown in the following table:

Date HIV viral load (copies of the virus per milliliter)
4/11/05 160
6/23/05 228
7/19/05 225
8/29/05 START OF GenoMed's TRIAL
11/2005 0
12/2005 0
1/2006 Switch from Sustiva(R) to Kaletra(R), which had failed this
patient in the past
2/14/06 109

Said Dr. David Moskowitz, GenoMed's CEO and Chief Medical Officer, 'In this trial, we've been using blood pressure pills, for which we have a 'use' patent that is pending. Why this should work is as interesting as the fact that it has worked. It points out the clinical reliability of the genomic epidemiologic data that we published in 2002.'

Continued Dr. Moskowitz, 'Our approach, if it is confirmed in other HIV patients, may help with the chronic treatment of HIV patients. Our earlier data suggests that this approach may also decrease infectivity of the HIV virus in the first place. Because these drugs already are on the shelves in most pharmacies on earth, including Africa, it could be quite helpful in the global struggle against HIV/AIDS.'

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From: jmhollen3/1/2006 1:16:15 PM
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GenoMed Awarded Second Patent, for Avoiding Dialysis in Acute Kidney Failure

Contact: David W. Moskowitz MD CEO, GenoMed tel. 314.983.9933 dwmoskowitz@genomed.com


ST. LOUIS—March 1, 2006--GenoMed (OTC Pink Sheets GMED), a Next Generation Disease Management company whose business is public health™, announced today that it received its second patent (US Patent #6,998,404) for the "Treatment or prevention of acute renal failure." Acute kidney failure usually happens when a patient gets dehydrated.

Acute kidney failure currently requires a lengthy hospital stay, often involving daily kidney dialysis in the Intensive Care Unit. In addition to the extra cost, acute kidney failure also carries up to a 50% risk of dying. Avoiding dialysis in the first place should greatly improve patient survival and lower healthcare costs.

Said David Moskowitz, MD, FACP, GenoMed's CEO and Chief Medical Officer, "Our patented protocol should be of immediate use to every hospital around the world, especially in places without convenient dialysis. It should be especially useful in disaster zones like New Orleans and earthquakes, as well as the battlefield, where people get dehydrated and go into kidney failure, but can't be dialyzed right away."

Added Dr. Moskowitz, "In a pilot series, our protocol was safe and effective in a dozen newborns and nine adults, including several patients with combined liver and kidney failure, so-called hepato-renal syndrome. We invite interested physicians to collaborate with us in extending these results to additional patients."

About GenoMed

GenoMed finds disease-causing genes, and uses this knowledge to devise new treatment strategies. The Company uses already existing medications whenever possible to maximize safety as well as minimize development costs. GenoMed then passes these savings on to healthcare consumers. GenoMed's treatment for acute kidney failure uses an already existing intravenous medication. An oral form may also work, which would be especially useful in natural disasters and the battlefield.


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From: jmhollen3/8/2006 3:16:13 PM
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GenoMed Announces Healthchip® to Predict Six Common Cancers Including Lung Cancer

Contact: David W. Moskowitz MD CEO, GenoMed tel. 314.983.9933 dwmoskowitz@genomed.com

ST. LOUIS—March 8, 2006--GenoMed (OTC Pink Sheets GMED.PK), a Next Generation Disease Management company whose business is public health™, announced today that it has developed a genomic test for predicting six common cancers: breast, colon, lung, ovarian, pancreatic, and prostate.

GenoMed's test, called the Healthchip®, consists of several hundred single nucleotide polymorphisms (SNPs, pronounced "snips"). Although several more years of tests will be required before FDA approval, the Healthchip® currently identifies patients correctly 85% of the time.

The Healthchip® allows patients to focus their preventive efforts on a single organ. A patient identified as "high risk" for lung cancer, such as Dana Reeve, could get an MRI of her lungs every year or two with the hope that any tumor would be detected at an early enough stage that it could be completely cut out surgically for a cure. Patients at high risk for a particular cancer would need to engage in lifelong surveillance, just as patients at risk for colon cancer undergo repeated colonoscopies their entire life.

Many of the genes that cause cancer will also make excellent targets for new chemotherapy drugs. Because they are more specific to the cancer process, these drugs promise to be less toxic than the currently employed general cellular poisons.

Said Dr. David Moskowitz, GenoMed's CEO and Chief Medical Officer, "Screening for the six cancers is currently possible in Caucasians only. We would like to extend this work to African American, Asian, and Hispanic patients. We would also like to extend our Healthchip® to include more than the top six solid cancers in adults, as well as cancers in children. Anyone interested is encouraged to contact me at 314.983.9933 or by e-mail, dwmoskowitz@genomed.com ."

About GenoMed

GenoMed finds disease-causing genes, and uses this knowledge to devise new treatment strategies. The Healthchip® is available on a research basis only. Because of genotyping costs, the Healthchip® costs $1,000 for research participants.
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From: jmhollen3/9/2006 3:21:13 PM
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GenoMed's Message for First World Kidney Day: 90% of Kidney Failure in U.S. Can Be Prevented Now

Contact: David W. Moskowitz MD CEO, GenoMed tel. 314.983.9933 dwmoskowitz@genomed.com


ST. LOUIS—March 9, 2006--GenoMed (OTC Pink Sheets GMED.PK), a Next Generation Disease Management company whose business is public health, announced today on the eve of the first World Kidney Day that it can prevent up to 90% of chronic kidney disease in the United States.

In September, 2002, GenoMed published a peer-reviewed medical article showing how chronic kidney disease due to diabetes and high blood pressure could be prevented in a total of 1,000 white and black male veterans from St. Louis. In unpublished data, GenoMed's Chief Medical Officer has prevented kidney failure in 350 Hispanic men and women followed since July, 2001 at a free clinic in St. Louis (La Clinica).

Diabetes and high blood pressure account for 90% of kidney dialysis patients in the United States. Medicare currently spends about $25 billion annually on dialysis and kidney transplantation for about 300,000 patients with kidney failure. Since 2000, kidney failure has been increasing at an epidemic rate, 7% per year.

Recovery of kidney function is not possible once a patient is on dialysis. There is a very narrow window of opportunity when prevention is possible: before the patient has lost more than half of their kidney function, that is, when their serum creatinine is still less than 2. (A normal serum creatinine is 1; when it's 10, it's time for dialysis).

Patients are still being seen by their primary care providers below a serum creatinine of 2, and haven't yet seen a kidney doctor. So education of patients and their primary care providers--general internists and family practitioners--is absolutely critical.

Said Dr. David Moskowitz, GenoMed's CEO and Chief Medical Officer, "It is fitting that the first World Kidney Day should fall during America's National Patient Safety Week. People of color throughout the world, including the U.S., are even more affected by kidney failure than whites."

Dr. Moskowitz continued, "I am deeply honored to be named today a Defender of Patient Safety by Missouri Watch (http://www.missouriwatch.net). The only thing needed to keep patients off dialysis is just to let them know that it can be done. It's unfortunate that it has taken over three years for the news to get this far. A whole generation of patients who could have been kept off the kidney machine three years ago has gone on to dialysis and an early death."

About GenoMed

GenoMed discovers the genes that cause disease and uses this knowledge to improve patient outcomes. The company's primary commitment is to public health, which involves public education. In addition to having treatments for acute and chronic kidney failure, emphysema, and autoimmune diseases such as psoriasis and alopecia, GenoMed has developed a broad-spectrum anti-viral approach that is expected to work for avian influenza, and has already worked for West Nile virus. GenoMed's anti-viral treatment is specifically mentioned in BioShield II, scheduled for debate this summer in the US Senate (see Section 2151 of Senate bill S. 975). To enroll in GenoMed's free clinical trial for avian influenza or West Nile virus, which uses existing, extremely safe medication already present in every drug store on earth, just go to www.genomed.com and click on the link for either trial.


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From: jmhollen4/12/2006 1:02:22 PM
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GenoMed Agrees to Distribute Healthcare to India for Under $150 Per Patient Per Year

FOR IMMEDIATE RELEASE

Contact:

David Moskowitz MD
CEO, GenoMed, Inc.
St. Louis, Missouri
www.genomed.com
Tel. 314-983-9933
Email: dwmoskowitz@genomed.com

Ms. Sujata Mital
Director, SUMIT Exports & Trades pvt. Ltd.
Mumbai, India
www.sumitbiomedical.com
Email: sumit_exports@yahoo.com

ST. LOUIS, April 12, 2006 -- GenoMed, Inc. (Pink Sheets GMED) a Next Generation Disease Management company whose business is public health™, announced today that it has entered into an exclusive agreement with SUMIT Exports & Trades to market its services to India for under US $150 per patient per year. Since the per capita income in India is around $600 a year, GenoMed has priced its Next Generation DM™ service within reach of the average Indian citizen.

Dr. David Moskowitz, GenoMed's CEO and Chief Medical Officer, said, "In 2002, we published that we can reverse chronic kidney failure from diabetes and high blood pressure, as well as significantly delay the progression of emphysema. Third World countries like India want to enjoy better health, but can't afford to spend $2 trillion a year on healthcare as the U.S. currently does. Thanks to medical genomics, GenoMed can already deliver better outcomes for cardiovascular disease, which two-thirds of people in First World countries like the U.S. die of. And we have a good jump on cancer, which a third of Americans die of."

Continued Dr. Moskowitz, "Yesterday, at the BIO 2006 convention in Chicago, former President Clinton called biotechnology the answer to international healthcare. Today, we're delighted to prove him right. We look forward to the expansion of President Bush's Health Savings Accounts (HSA's) to make preventive molecular medicine and lower health care costs a reality in the United States one day, too."

About GenoMed™

GenoMed is the only biotechnology company serious about both lowering healthcare costs and improving patient outcomes. It is leading the clinical revolution made possible by knowing which genes cause which diseases. GenoMed is currently marketing its protocols to prevent kidney failure due to high blood pressure and diabetes, and to delay the progression of emphysema. The company is offering its Healthchip®, on a research basis only, to predict breast, colon, lung, ovarian, pancreatic, and prostate cancer in Caucasians. And GenoMed is in the process of creating a virtual pharmaceutical company to develop new drugs for the hundreds of cancer chemotherapy targets it has discovered, in situations where no drug yet exists.


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From: jmhollen4/19/2006 9:52:11 AM
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GenoMed to Offer Free Mumps Trial

Contact: David Moskowitz MD
CEO, GenoMed, Inc.
Tel. 314-983-9938
Email: dwmoskowitz@genomed.com

ST. LOUIS—April 19, 2006--GenoMed Inc.-- ("the Company" or "GenoMed") (National Quotation Bureau's Pink Sheets Symbol: GMED.PK) a St. Louis, Missouri-based Next Generation Disease Management company whose business is public health™, announced today that it is offering a free clinical trial for mumps, using already existing medications. (The cost of the drugs, about $1 a day, is extra).

GenoMed believes a class of safe, already existing blood pressure pills may be a near-universal viral antidote, making vaccines and antiviral drugs unnecessary for most viruses except for the tiny fraction of the population which is immunosuppressed. GenoMed's approach has been successful for treating West Nile virus encephalitis in humans for the past 3 summers, and in birds for the past 2 summers. The first 8 patients were published in a peer-reviewed medical journal in 2004.

Said David Moskowitz, MD, GenoMed's CEO and Chief Medical Officer, "Unlike West Nile virus, the mumps virus is no more lethal than the common cold, but it causes a lot of discomfort. As with most viruses, disease in humans is caused by a 'cytokine storm,' not by the virus itself. Our approach is to calm the 'cytokine storm' in the host and ignore the virus. Our goal is to turn the patient into an asymptomatic shedder, which is what happens normally."

Added Dr. Moskowitz, "Our approach should work for most viruses in most people and animals. The more experience we get with different viruses, the more credible this approach becomes, and the readier we'll be for something really big, like avian flu or a viral bioterrorist attack."

GenoMed holds a pending patent for its approach in the U.S. but not the rest of the world. It was included in the Project BioShield Act of 2005 co-sponsored by Senators Lieberman, Hatch, and Brownback (see Section 2151 of Senate bill S.975, available at: govtrack.us. Introduced a year ago, this bill has not yet been discussed. The White House requested a briefing about GenoMed's possible viral antidote in the summer of 2004, and the Department of Homeland Security and the National Institutes of Health agreed to a briefing in the fall of that year. For the past three years, the World Health Organization has not returned any phone calls or emails on this subject. The Centers for Disease Control complained to the FDA about GenoMed's West Nile virus trial in June, 2004, but the FDA dropped the case as soon as it began investigating it in August, 2005.

To enroll in GenoMed's free clinical trial for mumps, simply contact Dr. Moskowitz.

About GenoMed

GenoMed is a Next Generation DM(tm) company that has found what it believes to be the "master" disease gene. It has already been able to prevent kidney failure due to diabetes and hypertension in whites, blacks and Hispanics; dramatically delay the progression of end-stage emphysema; and begin to see success in treating cancer and autoimmune diseases. GenoMed's near-universal viral antidote is simply another consequence of the "master" disease gene, which alone promises to revolutionize healthcare globally. Despite the usual obstacles facing any biotech start-up company, GenoMed perseveres in its mission to improve public health through genomics, promising a significant return to both patients and shareholders.

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From: Tadsamillionaire5/12/2006 9:05:12 PM
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MO Rep. Mott Oxford Congratulates GenoMed on Reversing Kidney Failure
ST. LOUIS, May 2 /PRNewswire-FirstCall/ -- GenoMed (Pink Sheets: GMED), a Next Generation Disease Management company whose business is public health(TM), announced today that Missouri State Representative Jeanette Mott Oxford has offered her congratulations to GenoMed on its novel treatment for chronic kidney failure.

GenoMed was the first to prove that chronic kidney failure may not be so chronic after all, at least early in its course. GenoMed's CEO, David Moskowitz MD, showed that chronic kidney failure due to diabetes or high blood pressure can actually be reversed early in the course of the disease.

Said the Honorable Ms. Mott Oxford, Representative for Missouri's 59th House District, 'Prevention of dialysis will save federal dollars and allow a much better quality of life for Missourians. The State of Missouri will benefit from healthier, more productive people who can continue to help others, rather than be a burden themselves.'

Rep. Mott Oxford continued, 'I am particularly excited by the implication this has for our state Medicaid budget. If kidney disease from diabetes and high blood pressure can be controlled, then maybe heart disease and other complications can be, too. If so, the cost of cardiovascular disease could finally be reduced in Missouri.'

Rep. Mott Oxford added, 'Dr. Moskowitz came to my attention a few years ago when he fought for a friend of mine with emphysema to receive proper treatment in a system that wanted to deny him needed medicines. As time has passed, my admiration has only grown.'

Dr. Moskowitz was recently presented with the 2006 Defender of Patient Safety Award (physician category) by Missouri Watch ( missouriwatch.net ). His results were published in Diabetes Technology and Therapeutics, a peer-reviewed medical journal, in September, 2002. If applied nationally, Dr. Moskowitz's method could prevent up to 90% of dialysis, and save Medicare over $22 billion a year. GenoMed owns the patents pending for this novel treatment approach

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