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Biotech / Medical : Incyte (INCY)
INCY 94.57+0.6%3:59 PM EST

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To: scaram(o)uche who wrote (3190)6/15/2018 4:19:21 PM
From: Miljenko Zuanic   of 3202
 
bloodjournal.org

< In an age- and sex-matched control group with none or conventional therapy (N=44), 7 patients (15.9%) tested positive for IgR (Figure 1E). This indicates the presence of clonal B-cells in the bone marrow of approximately 15% of PMF patients regardless of treatment.>

So, IF statics hold (for JAK1/2 involvement in progression to cancer), 1/3 of those clone identified may develop aB-cL on treatment? That is bad!

RE: REGN This is somehow positive for REGN, because all those a-topic allergic conditions that may be targeted with selective JAK1 may be "At risk" for B-CL!
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