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Biotech / Medical : Immunomedics (IMMU) - moderated
IMMU 20.59+11.3%Dec 6 4:00 PM EST

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To: drtom1234 who wrote (45929)4/27/2018 9:09:22 PM
From: weatherproof7 Recommendations

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My thought is that they set out accruing a minimal amount of patients for the first stage in a 2-stage phase II. It is my sense that the response rate in both urothelial and hormone positive BC were high enough to reject the null hypothesis (drug inactive due to lower than a predetermined response rate.) I'm also doubtful that the trial was stopped for efficacy. I think we're just seeing the trial suspended as they take the numbers from the basket trial representing stage one, and now determining the sample size, and such, for the second stage. The bad news would have been that they're not proceeding with the second stage due to inactivity of the drug or some issue with toxicity. I don't believe we're seeing any signs of that.
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