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Biotech / Medical : Incyte (INCY)
INCY 60.98+0.3%2:45 PM EDT

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To: former_pgs who wrote (3155)1/9/2018 3:29:40 PM
From: scaram(o)uche  Read Replies (1) of 3202
 
These findings are important translationally, because they suggest broader clinical uses for D-1MT against cancers that overexpress any tryptophan catabolic enzyme (IDO1, IDO2 or TDO).

ncbi.nlm.nih.gov

>> does suggest one would make a mistake by extrapolating heavily based on the indoximod data <<

Yeah, but a mistake in which direction?? Isn't downstream inhibition of IDO1, IDO2 and TDO better than IDO1 alone??

The Incyte rationale for IOD1 selective agents is given here, third paragraph.....

ncbi.nlm.nih.gov

So they would say "no".
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