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Biotech / Medical : Geron Corp.

GERN 4.510

+1.3%

Sep 13 9:30 AM EDT

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From: Casaubon	4/22/2012 1:15:04 PM
	1 Recommendation of 3566

DePinho and Sahin recently published on the adaptive mechanisms provoked by anti-telomerase therapy: Cell, 2012, v.148, p.651 If anyone is interested in discussing the ramifications to GERN, I would be interested in participating in that conversation. Topics of interest would include how the FDA would respond to the potential for driving a resistance mechanism, given the potential for a sustained positive response in a subset of patients. Also, of interest would be potential oxidative defense drugs, which could be utilized in combination with anti-telomerase therapy, to potentially increase the efficacy of GRN163L.

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