Biotech / Medical
An SI Board Since October 2009
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14 12 0 ZIOP
Emcee:  Biocaptain Type:  Moderated
Ziopharm is an oncology-focused company with 3 portfolio products:

1) Darinaparsin, an organic arsenic derivative with in vitro activity against lung, colon, brain, melanoma, ovarian and kidney cancers; hematological cancers (leukemia, lymphoma, myelodysplastic syndromes and multiple myeloma); does not have the cardiac, neurologic or hepatic toxicity of organic arsenic

ASCO 2009: encouraging data in refractory T-cell lymphoma; NHL
Composition of matter patent: expires 2022 (many additional patents)

2) Palifosfamide--Ifosfamide metabolite without the renal and bladder toxicity of Ifosfamide and without the "fuzzy brain" of cyclophasphamide; activity against a wide range of solid tumors

Oct 2009--Phase 2 sarcoma trial stopped early due to better than anticipated efficacy
Composition of matter patent: expires in 2018

3) Indibulin--tubulin antagonist with activity against a wide range of solid tumors

phase 1/2 trial in triple-negative breast cancer due to start Q1 of 2010
Composition of matter patent: expires in 2016; 3 methods of use patents, longest of which is out to 2026
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ReplyMessage PreviewFromRecsPosted Pivotal, randomized control trial in rGBM to initiate by end oThe Ox-November 7
13Apparently, ZIOP has finally recognized the error of their ways and decided to rPLegee-March 28
12Totally frustrated. So hard to get any information on this stock. No conferencPLegee-March 21
11Two big days in a row, I have no idea why, no news, but I like it!! Still thinkPLegee-February 3
10I guess I was wrong about warrants, there does not seem to be any. There was a The Ox-February 3
9Did not know there were warrants outstanding, thanks for that info. On another PLegee-February 2
8The run from $2 to $14 was pretty amazing but was way overdone, IMO. Had the stThe Ox-February 2
7Already 2M shares traded with still 2 hours of market before the close. Stock cPLegee-February 2
6 [graphic] [graphic]The Ox-February 1
5Of the two non-clinical obstacles in Ziop's price performance path (sector/pPLegee-February 1
4From the recent (Jan '17) JPM Healthcare Conference in San Francisco, ZIOP hPLegee1January 26
37:13AM ZIOPHARM reports Phase 3 trial of ZIOPHARM'S palifosfamide in first-lThe Ox-2/12/2013
2Palifosfamide data expected on Friday and based on the excitement exuded by the jeffpaley-11/4/2009
1Hi all Started this post tonight to highlight what I think is an unusual companBiocaptain-10/28/2009
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