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From: LindyBill2/28/2012 5:35:00 PM
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I have been posting about this from "day one." The thing to remember is, "don 't let the warnings scare you off.' Just be aware of the possible side effects and take action if you have any.

Safety Alerts Cite Cholesterol Drugs’ Side Effects By GARDINER HARRIS Published: February 28, 2012


NEW YORK TIMES



Federal health officials on Tuesday added new safety alerts to statins, cholesterol-reducing medications that are among the most widely prescribed drugs in the world, citing the rare risks of memory loss, increased blood sugar levels and muscle pain.

It is the first time that the Food and Drug Administration has officially linked statin use with cognitive problems like forgetfulness and confusion, although some patients have reported such problems for years. Among the drugs affected are such huge sellers as Lipitor, Zocor, Crestor and Vytorin.

Numerous studies have shown that statin therapy decreases the risk of death in high-risk patients, but debate has raged for years about whether those at moderate risk for heart problems should be placed on statin therapy. The federal alerts about the risks of statin therapy are likely to cheer those who have insisted that statin therapy should not be recommended to patients who are not at high risk of heart disease or heart attack.

Still, Dr. Amy G. Egan, deputy director for safety in the F.D.A.’s division of metabolism and endocrinology products, said that the new safety alerts should not scare people away from statins. “The value of statins in preventing heart disease has been clearly established,” she said. “Their benefit is indisputable, but they need to be taken with care and knowledge of their side effects.”

The F.D.A. also said that routine monitoring of liver enzymes in the blood, once considered standard procedure for statin users, is no longer needed because the liver injury associated with statin therapy is so rare.

Reports about memory loss, forgetfulness and confusion span all statin drugs and all age groups of patients, the F.D.A. said. Dr. Egan said the reports were rare, but those affected often feel “fuzzy” or unfocused in their thinking.

The symptoms generally were not serious and went away within a few weeks after patients stopped taking the medications. Some people affected had been taking a statin for a day, others for years.

That statins may increase blood sugar levels is worrisome because this side effect increases the risk of developing Type 2, or adult-onset, diabetes. Dr. Egan said the benefits of statins still outweighed the relatively small increased risk of diabetes, but she suggested that doctors check the blood sugar levels of patients after starting them on statin therapy.

That statins can cause muscle pain in patients, particularly at high doses, has long been known, but in its new alert the F.D.A. reminded doctors that some other medications increase the likelihood that statins linger in the body longer than normal and increase the risk of muscle pain.

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To: LindyBill who wrote (17314)2/28/2012 7:35:35 PM
From: r.edwards
   of 28400
 
just received my blood work from a week ago.. Cholesterol Total 194, HDL 52, Triglycerides 202H, LDL 102
Chol/HDLC Ratio 3.7.... wish I knew what that means....... Now to work on the HDL over the next six months.

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To: Newly2b who wrote (18628)2/28/2012 7:47:58 PM
From: r.edwards
1 Recommendation   of 28400
 
I need to get off wheat, and flour carbs, get some fish oil, get some CQ10, and exercise , I guess, to get the HDL up !!!

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To: r.edwards who wrote (18631)2/28/2012 8:19:09 PM
From: Newly2b
1 Recommendation   of 28400
 
You really need to get your trigs down, that is more important with your numbers than bringing your HDL up IMO. High trigs are associated with obesity, high levels of inflammatory proteins in the blood, high BP and diabetes, and usually mean lower HDL and it combines with LDL to cause plaque. Also causes pancreatitis..That said, if you do get off wheat, start taking fish oil, COQ10 and D3, that's a good start. There's a lot more, but that'll come to you as you begin looking around and learning what you need to know. I would also suggest that next time you ask for an Advanced Lipid Profile from Labcorp (called an NMR LipoProfile), including your Insulin Resistance Score (LP-IR Score) and test your Lp(a). This will give you a much better picture of where you are with your cholesterol and whether or not it is a problem. My cholesterol is way higher than yours but my LDL size is 92% large, bouyant so I'm not worried by the higher number plus my trigs are exceptionally low and my HDL exceptionally high.

Here's what I listed as helpful during my years of research re lower cholesterol:

Fish oil helps lowers trigs.
Losing weight helps
quit eating wheat
eat almonds, walnuts, pistachios and oatmeal
Fiber is good (oat bran, flaxseed)
Flavonoids and polyphenols (oolong tea)
garlic (can get in capsules if you don't want your breath to stink)
Supposedly Niacin helps reduce LDL, but it doesn't seem to do that with mine, which is quite high and I take Niacin 500 mg every day.
Soy is also said to help but has other drawbacks.
Vitamins E also reduces LDL but I've read some bad stuff about it.
Vegetable oils are bad, use only extra virgin olive oil.
Exercise
Lecithin may help, too

Just some ideas. Good luck to you.

Newly

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To: Newly2b who wrote (18632)2/28/2012 8:34:49 PM
From: r.edwards
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Thanks Newly2b, will do,....... my job is super high stress the last 5 years, which does not help either,..... but I believe I have some good things about to happen in the next 3 months or so by June , which may allow me a completely different lifestyle.

Freedom to exercise, and more financial freedom, hopefully attitude will be lifted.

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To: r.edwards who wrote (18631)2/28/2012 8:52:47 PM
From: Travis_Bickle
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Fish oil is the easiest of the lot, they sell it everywhere and it's cheap.

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To: Travis_Bickle who wrote (18634)2/28/2012 9:13:24 PM
From: r.edwards
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Thanks Travis, going to "Sprouts" late tomorrow.

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To: r.edwards who wrote (18633)2/28/2012 9:40:44 PM
From: Newly2b
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I certainly hope so for your sake! Stress kills! Of course, we can never eliminate it completely, being alive is stressful, but we can try to keep it at non-lethal levels if possible.

Newly

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To: Les H who wrote (18122)2/28/2012 10:19:57 PM
From: Les H
2 Recommendations   of 28400
 
FDA adds diabetes, memory loss warnings to statins
By Bill Berkrot and Ransdell Pierson
Tue Feb 28, 2012 5:29pm EST

reuters.com

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To: Newly2b who wrote (18632)2/28/2012 11:24:44 PM
From: ig
   of 28400
 
Newly, you're a treasure. Thanks again.

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