|IS anyone else still interested in LEXG? I was generally impressed by the J P Morgan presentation. One thing has bothered me from the beginning though, what's the function of a gene for stupidity? Their lead, compound LG617, knocks out a gene, and this makes mice quicker to learn and slower to forget. |
Why did the gene evolve? What benefit does it confer? Do brighter mice succumb to existential angst and commit suicide, or do nerd mice find it harder to get mates?
They expect to be out of preclinical studies by mid 2006 and plan to start on humans then. I wouldn't want to be part of any trial for this drug, and I could certainly do with being brighter!